|
|
|
Karthik Sambanthamoorthy, Ph.D.
Education
|
1999
|
|
B.Sc., Microbiology, University of Madras, India
|
|
2001
|
|
M.Sc., Microbiology, University of Madras, India
|
|
2007
|
|
Ph.D., Microbiology, The University of Southern Mississippi,
USA
|
|
2007-Present
|
|
Research Fellow, Center for Genomic Sciences, Allegheny-Singer
Research Institute, Pittsburgh, PA, USA
|
Research Interests
- Molecular mechanisms of
microbial pathogenesis and antimicrobial resistance
- Host pathogen interactions
- Biofilm biology and molecular
mechanisms of biofilm formation.
- Biofilm control on medical
devices
Current Projects
- Applied research program with
Bayer to characterize the anti-biofilm properties of ablatable surfaces
- Staphylococcal pathogenesis
and biofilms
- Regulation of biofilm
formation in Pseudomonas aeruginosa
- Streptococcus pneumoniae biofilms
Professional Memberships
- American Society for
Microbiology
- Society for General
Microbiology
- American Association for the
Advancement of Science (AAAS)
- Associate Member of
Bioinformatics Organization
- Mississippi Academy of
Sciences
Awards/Honors
|
2002-04
|
|
NSF-Materials Research Science and Engineering Center (MRSEC)
Research Assistantship
|
|
2004-05
|
|
Biological Sciences Graduate Teaching Assistantship, The
University of Southern Mississippi
|
|
2005
|
|
Recipient of the University of Southern Mississippi Travel grant
for the 105th General Meeting, Atlanta, GA, USA
|
|
2005-07
|
|
Mississippi Functional Genomics Network (MFGN) Research
Fellowship
|
|
2007
|
|
American Society for Microbiology Corporate Student Travel Grant
Award for the 107th General Meeting, Toronto, Canada
|
|
2007
|
|
Post-Doctoral Research Fellowship, Center for Genomic
Sciences, Allegheny-Singer Research Institute, Pittsburgh, PA, USA
|
Media Articles
|
2007
|
|
WDAM-TV, an NBC affiliate
|
|
2007
|
|
"USM Researchers Aim To Stop Staph" in WLOX-TV, an
ABC affiliate
|
|
2007
|
|
"Staph infection may cause lesions" in Sunherald.com
|
|
2007
|
|
"USM team aims to stop staph" "Hattiesburg
American" Daily Newspaper in Mississippi
|
|
2007
|
|
"Research prevails" in The Student Printz. The
University of Southern Mississippi
|
|
2007
|
|
"Researchers Combating Antibiotic-Resistant Staph
Infections" in Department of Marketing and Public Relations. The
University of Southern Mississippi
|
|
2007
|
|
"Skin Lesions may be caused by staph infection, doctors
say" at the Times Picayune (affiliate website www.nola.com)
|
|
2007
|
|
"USM researchers strike blow in war against staph"
in Clarionledger.com
|
|
2007
|
|
"Infectious germ goes from bad to worse" in
Sunherald.com
|
|
2007
|
|
"USM professor studies staph to help create a super
drug" in Sunherald.com
|
|
2007
|
|
"Infectious Concern" in Times Picayune Nola
|
Conference Presentations
1. Karthik Sambanthamoorthy and Mohamed O.
Elasri. 2003. Characterization of the genes involved in the pathogenesis of Staphylococcus
aureus. Annual Biological Sciences Graduate Research Symposium. March 22
"03". Hattiesburg. Mississippi. (PLATFORM)
2. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2003. Characterization of
genes involved in the pathogenesis of Staphylococcus aureus. Annual
Meeting. American Society for Microbiology- South Central Branch. Oct 24
"03". New Orleans. LA. (PLATFORM)
3. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2003. Modification of
Surfaces to Prevent Biofilm Formation by Staphylococcus aureus. NSF
Materials Research Science and Engineering Center (MRSEC) Annual Graduate
Research Symposium. Nov 6 "03". Hattiesburg. Mississippi. (POSTER)
4. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Regulation of
Virulence Factors in Staphylooccus aureus. Feb 19 "04". 68th Annual
Meeting of the Mississippi Academy of Sciences. Biloxi. Mississippi.
(PLATFORM)
5. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Regulation of
Virulence Factors in Staphylooccus aureus. Annual Biological Sciences
Graduate Research Symposium. March 22 "04". Hattiesburg.
Mississippi. (PLATFORM)
6. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Regulation of
Virulence Factors in Staphylooccus aureus. Annual Meeting. American Society
for Microbiology- South Central Branch. Nov 05 "04". Starkville.
Mississippi. (PLATFORM).
7. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Modification of
Surfaces to Prevent Biofilm Formation by Staphylococcus aureus. NSF
Materials Research Science and Engineering Center (MRSEC). Annual Graduate
Research Symposium. Nov 10 "04". Hattiesburg. Mississippi. (POSTER)
8. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2005. Characterization of
Novel Virulence Factors in Staphylooccus aureus. Feb 19 "05". 69th
Annual Meeting of the Mississippi Academy of Sciences. Oxford. Mississippi.
(PLATFORM)
9. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2005. Characterization of
Novel Virulence Factors in Staphylooccus aureus. Annual Biological Sciences
Graduate Research Symposium. March 22 "05". Hattiesburg.
Mississippi. (PLATFORM)
10. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006. Regulation of
Staphylococcus Accessory Regulator (sarA) in Staphylococcus aureus.
Feb 22 "06". 70th Annual Meeting of the Mississippi Academy of
Sciences. Vicksburg. Mississippi. (PLATFORM)
11. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006 (Meeting for
cancelled year 2005). Regulation of Virulence Factors in Staphylooccus
aureus. Annual Meeting. American Society for Microbiology- South Central
Branch. Mar 04 "06". La Fayette. Louisiana. (PLATFORM)
12. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006. Accessory Elements
Involved in Global Regulation of Virulence in Staphylococcus aureus.
Annual Biological Sciences Graduate Research Symposium. Apr 01
"06". Hattiesburg. Mississippi. (PLATFORM)
13. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006. Role of msa
in Bioflm Formation in Staphylooccus aureus. Annual Meeting. American Society
for Microbiology- South Central Branch. Nov 03 "06". Baton Rouge.
Louisiana. (PLATFORM)
14. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2007. Role of msa
in Regulating Bioflm Formation in Staphylooccus aureus. 71th Annual Meeting
of the Mississippi Academy of Sciences. Feb 21 "07" Starkville.
Mississippi. (PLATFORM)
15. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2007. Role of msa
in regulating virulence and biofilm formation in Staphylococcus aureus.Annual
Biological Sciences Graduate Research Symposium. Apr "07".
Hattiesburg. Mississippi. (PLATFORM)
16. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2007. msa Plays an
Important Role in Biofilm Formation in Staphylococcus aureus. 107th
General Meeting of American Society for Microbiology. May 21-25
"07" Toronto, Canada. (POSTER)
17. Karthik Sambanthamoorthy, Laura Nistico, Mark Longwell, N. Mehta, S.
Kathju, L. Hall-Stoodley, P. Stoodley, F. Hu, G.D. Ehrlich and C.J. Post. 2007.
Microbial Biofilm Research at the Center for Genomic Sciences. Oct 03
"07". Philadelphia, Pennsylvania. (POSTER)
18. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. Biofilm
formation is regulated by msa in Staphylococcus aureus. 72nd
Annual Mississippi Academy of Sciences Meeting. Whispering Woods Hotel and
Conference Center. Feb "08". Olive Branch, Mississippi. (PLATFORM)
19. Karthik Sambanthamoorthy, Leslie-Ann Lasko, Paul Stoodley, Laura Nistico,
J. Christopher Post, Garth D. EhrlicH, and Sandeep Kathju. Biofilms in
orthopedic joint implant infection: in vitro and in vivo
studies. Fourth annual Bioimaging Day. Carnegie Mellon University. Feb
"08". Pittsburgh, Pennsylvania. (POSTER)
20. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. Biofilm
formation is regulated by msa in Staphylococcus aureus. 24th
Annual Biological Sciences Graduate Student Symposium. Mar "08".
Hattiesburg, Mississippi. (PLATFORM)
21. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. Biofilm
formation is regulated by msa in Staphylococcus aureus. 1st
Annual Graduate Research Symposium. Thad Cochran Conference Center. Apr
"08". Hattiesburg, Mississippi. (PLATFORM)
22. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. msa
regulates biofilm formation in Staphylococcus aureus. 108th American
Society for Microbiology General Meeting. Jun "08". Boston,
Massachusetts. (POSTER)
23. Karthik Sambanthamoorthy, Brian Zembruski, Duc Nguyen, Paul Stoodley,
Pranav Joshi, Hironobu Murata, Rick Koespel, Allan Russell, Paul Nowatzki,
Edwin Hortelano and G. Ehrlich. Assessment of Biofilm Formation by
Luminescent Bacteria and Evaluation of Bactericidal Activity Using a
High-Throughput Biofilm Testing Method.108th General Meeting of American
Society for Microbiology. June 1-5 "08" Boston, Massachusetts.
(POSTER)
Publications
Sambanthamoorthy K, Smeltzer MS, and Elasri
MO. Identification and
characterization of msa (SA1233), a gene involved in expression of
SarA and several virulence factors in Staphylococcus aureus.
Microbiology. 152; 2559-2572, 2006.
Sambanthamoorthy K. Role of msa in the regulation
of virulence and biofilm formation in Staphylococcus aureus. A Dissertation. 2007. The University
of Southern Mississippi.
Hall-Stoodley L, Nistico L,
Sambanthamoorthy K, Dice B, Nguyen D, Mershon WJ, Johnson C, Hu FZ, Stoodley
P, Ehrlich GD, Post JC.
Characterization of biofilm matrix, degradation by DNase treatment and
evidence of capsule downregulation in Streptococcus pneumoniae clinical
isolates. BMC Microbiol 8:173,
2008.
Karthik Sambanthamoorthy, Antony Schwartz and
Mohamed O. Elasri. Role of msa in the Accumulation of biofilm in Staphylococcus
aureus. (Submitted).
< Back
|