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We are part of the West Penn Allegheny Health System
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Karthik Sambanthamoorthy, Ph.D.
Education
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1999
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B.Sc., Microbiology, University of Madras, India
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2001
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M.Sc., Microbiology, University of Madras, India
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2007
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Ph.D., Microbiology, The University of Southern Mississippi, USA
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2007-Present
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Research Fellow, Center for Genomic Sciences, Allegheny-Singer Research Institute, Pittsburgh, PA, USA
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Research Interests
- Molecular mechanisms of microbial pathogenesis and antimicrobial resistance
- Host pathogen interactions
- Biofilm biology and molecular mechanisms of biofilm formation.
- Biofilm control on medical devices
Current Projects
- Applied research program with Bayer to characterize the anti-biofilm properties of ablatable surfaces
- Staphylococcal pathogenesis and biofilms
- Regulation of biofilm formation in Pseudomonas aeruginosa
- Streptococcus pneumoniae biofilms
Professional Memberships
- American Society for Microbiology
- Society for General Microbiology
- American Association for the Advancement of Science (AAAS)
- Associate Member of Bioinformatics Organization
- Mississippi Academy of Sciences
Awards/Honors
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2002-04
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NSF-Materials Research Science and Engineering Center (MRSEC) Research Assistantship
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2004-05
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Biological Sciences Graduate Teaching Assistantship, The University of Southern Mississippi
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2005
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Recipient of the University of Southern Mississippi Travel grant for the 105th General Meeting, Atlanta, GA, USA
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2005-07
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Mississippi Functional Genomics Network (MFGN) Research Fellowship
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2007
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American Society for Microbiology Corporate Student Travel Grant Award for the 107th General Meeting, Toronto, Canada
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2007
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Post-Doctoral Research Fellowship, Center for Genomic Sciences, Allegheny-Singer Research Institute, Pittsburgh, PA, USA
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Media Articles
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2007
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WDAM-TV, an NBC affiliate
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2007
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"USM Researchers Aim To Stop Staph" in WLOX-TV, an ABC affiliate
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2007
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"Staph infection may cause lesions" in Sunherald.com
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2007
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"USM team aims to stop staph" "Hattiesburg American" Daily Newspaper in Mississippi
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2007
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"Research prevails" in The Student Printz. The University of Southern Mississippi
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2007
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"Researchers Combating Antibiotic-Resistant Staph Infections" in Department of Marketing and Public Relations. The University of Southern Mississippi
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2007
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"Skin Lesions may be caused by staph infection, doctors say" at the Times Picayune (affiliate website www.nola.com)
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2007
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"USM researchers strike blow in war against staph" in Clarionledger.com
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2007
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"Infectious germ goes from bad to worse" in Sunherald.com
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2007
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"USM professor studies staph to help create a super drug" in Sunherald.com
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2007
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"Infectious Concern" in Times Picayune Nola
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Conference Presentations
1. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2003. Characterization of the genes involved in the pathogenesis of Staphylococcus aureus. Annual Biological Sciences Graduate Research Symposium. March 22 "03". Hattiesburg. Mississippi. (PLATFORM)
2. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2003. Characterization of genes involved in the pathogenesis of Staphylococcus aureus. Annual Meeting. American Society for Microbiology- South Central Branch. Oct 24 "03". New Orleans. LA. (PLATFORM)
3. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2003. Modification of Surfaces to Prevent Biofilm Formation by Staphylococcus aureus. NSF Materials Research Science and Engineering Center (MRSEC) Annual Graduate Research Symposium. Nov 6 "03". Hattiesburg. Mississippi. (POSTER)
4. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Regulation of Virulence Factors in Staphylooccus aureus. Feb 19 "04". 68th Annual Meeting of the Mississippi Academy of Sciences. Biloxi. Mississippi. (PLATFORM)
5. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Regulation of Virulence Factors in Staphylooccus aureus. Annual Biological Sciences Graduate Research Symposium. March 22 "04". Hattiesburg. Mississippi. (PLATFORM)
6. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Regulation of Virulence Factors in Staphylooccus aureus. Annual Meeting. American Society for Microbiology- South Central Branch. Nov 05 "04". Starkville. Mississippi. (PLATFORM).
7. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2004. Modification of Surfaces to Prevent Biofilm Formation by Staphylococcus aureus. NSF Materials Research Science and Engineering Center (MRSEC). Annual Graduate Research Symposium. Nov 10 "04". Hattiesburg. Mississippi. (POSTER)
8. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2005. Characterization of Novel Virulence Factors in Staphylooccus aureus. Feb 19 "05". 69th Annual Meeting of the Mississippi Academy of Sciences. Oxford. Mississippi. (PLATFORM)
9. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2005. Characterization of Novel Virulence Factors in Staphylooccus aureus. Annual Biological Sciences Graduate Research Symposium. March 22 "05". Hattiesburg. Mississippi. (PLATFORM)
10. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006. Regulation of Staphylococcus Accessory Regulator (sarA) in Staphylococcus aureus. Feb 22 "06". 70th Annual Meeting of the Mississippi Academy of Sciences. Vicksburg. Mississippi. (PLATFORM)
11. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006 (Meeting for cancelled year 2005). Regulation of Virulence Factors in Staphylooccus aureus. Annual Meeting. American Society for Microbiology- South Central Branch. Mar 04 "06". La Fayette. Louisiana. (PLATFORM)
12. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006. Accessory Elements Involved in Global Regulation of Virulence in Staphylococcus aureus. Annual Biological Sciences Graduate Research Symposium. Apr 01 "06". Hattiesburg. Mississippi. (PLATFORM)
13. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2006. Role of msa in Bioflm Formation in Staphylooccus aureus. Annual Meeting. American Society for Microbiology- South Central Branch. Nov 03 "06". Baton Rouge. Louisiana. (PLATFORM)
14. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2007. Role of msa in Regulating Bioflm Formation in Staphylooccus aureus. 71th Annual Meeting of the Mississippi Academy of Sciences. Feb 21 "07" Starkville. Mississippi. (PLATFORM)
15. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2007. Role of msa in regulating virulence and biofilm formation in Staphylococcus aureus.Annual Biological Sciences Graduate Research Symposium. Apr "07". Hattiesburg. Mississippi. (PLATFORM)
16. Karthik Sambanthamoorthy and Mohamed O. Elasri. 2007. msa Plays an Important Role in Biofilm Formation in Staphylococcus aureus. 107th General Meeting of American Society for Microbiology. May 21-25 "07" Toronto, Canada. (POSTER)
17. Karthik Sambanthamoorthy, Laura Nistico, Mark Longwell, N. Mehta, S. Kathju, L. Hall-Stoodley, P. Stoodley, F. Hu, G.D. Ehrlich and C.J. Post. 2007. Microbial Biofilm Research at the Center for Genomic Sciences. Oct 03 "07". Philadelphia, Pennsylvania. (POSTER)
18. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. Biofilm formation is regulated by msa in Staphylococcus aureus. 72nd Annual Mississippi Academy of Sciences Meeting. Whispering Woods Hotel and Conference Center. Feb "08". Olive Branch, Mississippi. (PLATFORM)
19. Karthik Sambanthamoorthy, Leslie-Ann Lasko, Paul Stoodley, Laura Nistico, J. Christopher Post, Garth D. EhrlicH, and Sandeep Kathju. Biofilms in orthopedic joint implant infection: in vitro and in vivo studies. Fourth annual Bioimaging Day. Carnegie Mellon University. Feb "08". Pittsburgh, Pennsylvania. (POSTER)
20. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. Biofilm formation is regulated by msa in Staphylococcus aureus. 24th Annual Biological Sciences Graduate Student Symposium. Mar "08". Hattiesburg, Mississippi. (PLATFORM)
21. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. Biofilm formation is regulated by msa in Staphylococcus aureus. 1st Annual Graduate Research Symposium. Thad Cochran Conference Center. Apr "08". Hattiesburg, Mississippi. (PLATFORM)
22. Antony Schwartz, Karthik Sambanthamoorthy and Mohamed O. Elasri. msa regulates biofilm formation in Staphylococcus aureus. 108th American Society for Microbiology General Meeting. Jun "08". Boston, Massachusetts. (POSTER)
23. Karthik Sambanthamoorthy, Brian Zembruski, Duc Nguyen, Paul Stoodley, Pranav Joshi, Hironobu Murata, Rick Koespel, Allan Russell, Paul Nowatzki, Edwin Hortelano and G. Ehrlich. Assessment of Biofilm Formation by Luminescent Bacteria and Evaluation of Bactericidal Activity Using a High-Throughput Biofilm Testing Method.108th General Meeting of American Society for Microbiology. June 1-5 "08" Boston, Massachusetts. (POSTER)
Publications
Sambanthamoorthy K, Smeltzer MS, and Elasri MO. Identification and characterization of msa (SA1233), a gene involved in expression of SarA and several virulence factors in Staphylococcus aureus. Microbiology. 152; 2559-2572, 2006.
Sambanthamoorthy K. Role of msa in the regulation of virulence and biofilm formation in Staphylococcus aureus. A Dissertation. 2007. The University of Southern Mississippi.
Hall-Stoodley L, Nistico L, Sambanthamoorthy K, Dice B, Nguyen D, Mershon WJ, Johnson C, Hu FZ, Stoodley P, Ehrlich GD, Post JC. Characterization of biofilm matrix, degradation by DNase treatment and evidence of capsule downregulation in Streptococcus pneumoniae clinical isolates. BMC Microbiol 8:173, 2008.
Karthik Sambanthamoorthy, Antony Schwartz and Mohamed O. Elasri. Role of msa in the Accumulation of biofilm in Staphylococcus aureus. (Submitted).
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