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We are part of the West Penn Allegheny Health System
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Kai Shen, M.D., Ph.D.
Education
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2001
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Research Fellow, Experimentelle Transplantationschirurgie, Universitätsklinikum Essen, Essen, Germany
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1997
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Ph.D., Department of Urology and Organ Transplantation Center, First University Hospital, Medical School, West China University of Medical Sciences, Chengdu, Sichuan, P.R.China
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1992
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M.D., Medical School, West China University of Medical Sciences, Chengdu, Sichuan, P.R.China
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Research Interests
- Bacterial biofilm studies
- Inherited cranial facial diseases
Current Projects
- Biofilms
- Crouzon syndrome and other inherited cranial facial diseases. Project in progress: Molecular Genetics of a Syndrome with Hearing Impairment.
Professional Memberships
Member of the China Red Cross Society
Candidate member of the World Transplantation Society
Honors & Awards
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1999
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Research Assistant Scholarship in Essen University, Germany
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1998
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Grant of European Association for the Study of the Liver (EASL)
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1996
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Zhan Zhen-sheng Scholarship of West China University of Medical Sciences
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1995
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Excellent PhD Student Award of the West China University of Medical Sciences
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1993
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Excellent Graduate Student Award of West China University of Medical Sciences
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Publications
Hiller NL, Janto B, Hogg JS, Boissy R, Yu S, Powell E, Keefe R, Ehrlich NE, Shen K, Hayes J, Barbadora K, Klimke W, Dernovoy D, Tatusova T, Parkhill J, Bentley SD, Post JC, Ehrlich GD, Hu FZ. Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: Insights into the pneumococcal supragenome 2. J Bacteriol, 2007, Accepted.
Erods G, Sayeed S, Hu FZ, Antalis PT, Shen K, Hayes JD, Ahmed AI, Johnson SL, Post JC, Ehrlich GD. Construction and characterization of a highly redundant Pseudomonas aeruginosa genomic library prepared from 12 clinical isolates: Application to studies of gene distribution among populations. Int J Pediatr Otorhinolaryngol 70:1891-1900, 2006.
Shen K, Sayeed S, Antalis P, Gladitz J, Ahmed A, Dice B, Janto B, Dopico R, Keefe R, Hayes J, Johnson S, Yu S, Ehrlich N, Jocz J, Kropp L, Wong R, Wadoowsky RM, Slifkin M, Preston RA, Erdos G, Post JC, Ehrlich GD, Hu FZ. Extensive genomic plasticity in Pseudomonas aeruginosa revealed by identification and distribution studies of novel genes among clinical isolates. Infect Immun 74(9):5272-5283, 2006.
Shen K, Gladitz J, Antalis P, Dice B, Janto B, Keefe R, Hayes J, Ahmed A, Dopico R, Ehrlich N, Jocz J, Kropp L, Yu S, Nistico L, Greenberg DP, Barbadora K, Preston RA, Post JC, Ehrlich GD, Hu FZ. Characterization, distribution and expression of novel genes among eight clinical isolates of Streptococcus pneumoniae. Infect Immun 74(1):321-330, 2006.
Ehrlich GD, Hu FZ, Shen K, Stoodley P, Post JC. Bacterial plurality as a general mechanism driving persistence in chronic infections. Clin Orthop 437;20-24, 2005.
Shen K, Antalis P, Gladitz J, Sayeed S, Ahmed A, Yu S, Hayes J, Johnson S, Dice B, Dopico R, Keefe R, Janto B, Chong W, Goodwin J, Wadowsky RM, Erdos G, Post JC, Ehrlich GD, Hu FZ. Identification, distribution, and expression of novel (nonRd) genes in ten clinical isolates of nontypeable Haemophilus influezae. Infect Immun 73;6:3479-3491, 2005.
Gladitz J, Shen K, Antalis P, Hu FZ, Post JC, Ehrlich GD. Codon usage comparison of novel genes in clinical isolates of Haemophilus influenzae. Nucleic Acids Res 33;11:3644-3658, 2005.
Li J, Dahmen U, Dirsch O, Shen K, Gu Y, Broelsch CE. Modified sleeve anastomosis for reconstruction of the hepatic artery in rat liver transplantation. Microsurgery 22(2): 62-8, 2002.
Dahmen U, Li J, Dirsch O, Shen K, Fan L, Gu Y, Doebel L, Broelsch CE. Induktion von Abstossung nach Lebertransplantation ist abhängig von der transplatatierten Lebermass. Chirurgie Forum. Band 29. S.199-204, 2000.
Shen K, Yang YR, Tang XD, Huang MK, Li H, Shen H, Lei S, Wei YQ, Zhang HY. Effect of vasectomy on apoptosis in spermatogenic cells of the male rat. Hua Xi Yi Ke Da Xue Xue Bao. 29(4): 403-407, 1998.
Shen K, Yang YR, Li YP. HBV infection in renal transplant recipients. Foreign Medical Sciences, Section of Urology 18(suppl): 85-87, 1998.
Shen K, Tang XD, Yang YR. D type cyclins and their relationship with oncogenes and tumor suppressor genes. Chinese J Medical Genetics 13(6): 361-365, 1996.
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