Center for Genomic Sciences

Home

Contact Us

Site Map

Help

 

About Us

Research

Education

Facilities

Faculty/Staff

Public Documents

Services

 

 



Find Out More...

Overview

New Research Directions

Educational Mission

 

Collaborations

Corporate Partnerships

Opportunities for Employment

Opportunities for Corporate Sponsorship


We are part of the West Penn Allegheny Health System

Recent Publications

In chronological order:

·         Gladitz J, Shen K, Antalis P, Hu FZ, Post JC, Ehrlich GD.  Codon usage comparison of novel genes in clinical isolates of Haemophilus influenzae.  Nucleic Acids Res 33;11:3644-3658, 2005.  Full article 

·         Shen K, Antalis P, Gladitz J, Sayeed S, Ahmed A, Yu S, Hayes J, Johnson S, Dice B, Dopico R, Keefe R, Janto B, Chong W, Goodwin J, Wadowsky RM, Erdos G, Post JC, Ehrlich GD, Hu FZ.  Identification, distribution, and expression of novel (nonRd) genes in ten clinical isolates of nontypeable Haemophilus influenzae.  Infect Immun 73;6:3479-3491, 2005.

·         Hu FZ, Nystrom A, Ahmed A, Palmquist M, Dopico R, Mossberg I, Gladitz J, Rayner M, Post JC, Ehrlich GD, Preston RA.  Mapping of an autosomal dominant gene for Dupuytren's contracture to chromosome 16q in a Swedish family. Clin Genet  68:424-429, 2005.

·         Post JC, Hu FZ, Ehrlich GD.  Genetics of pediatric gastroesophageal reflux.  Curr Opin Allergy Clin Immunol 5;1:5-9, 2005.

·         Stoodley P, Kathju S, Hu FZ, Erdos G, Levenson JE, Mehta N, Dice B, Johnson S, Hall-Stoodley L, Nistico L, Sotereanos N, Sewecke J, Post JC, Ehrlich GD.  Molecular and imaging techniques for bacterial biofilms in joint arthroplasty infections.  Clin Orthop 437:31-40, 2005. Full article 

·         Ehrlich GD, Hu FZ, Shen K, Stoodley P, Post JC.  Bacterial plurality as a general mechanism driving persistence in chronic infections.  Clin Orthop 437:20-24, 2005. Full article 

·         Ehrlich GD, Stoodley P, Kathju S, Zhao Y, Mcleod BR, Baliban N, Hu FZ, Sotereanos N, Costerton JW, Stewart PS, Post JC, Lin Q.  Engineering approaches for the detection and control of orthopaedic biofilm infections.  Clin Orthop 437:59-66, 2005.

·         Braxton E, Ehrlich G, Stoodley P, Hall-Stoodley L, Veeh R, Hu F, Fux C, Quigley M, Post JC.  The role of biofilms in neurosurgical device-related infections.  Neurosurg Rev 28;4:249-255, 2005.  Full article 

·         Sharp RR, Stoodley P, Adgie M, Gerlach R, Cunningham A.  Visualization and characterization of dynamic patterns of flow, growth and activity of biofilms growing in porous media.  Water Sci Technol 52;7:85-90, 2005.

·         Borriello G, Richards L, Ehrlich GD, Stewart PS.  Arginine or nitrate enhances antibiotic susceptibility of Pseudomonas aeruginosa in biofilms.  Antimicrob Agents Chemother 50;1:382-384, 2005.  Full article 

·         Shen K, Gladitz J, Antalis P, Dice B, Janto B, Keefe R, Hayes J, Ahmed A, Dopico R, Ehrlich N, Jocz J, Kropp L, Yu S, Nistico L, Greenberg DP, Barbadora K, Preston RA, Post JC, Ehrlich GD, Hu FZ.  Characterization, distribution and expression of novel genes among eight clinical isolates of Streptococcus pneumoniae.  Infect Immun 74;1:321-330, 2006.  Full article 

·         Fux CA, Quigley M, Worel AM, Post C, Zimmerli S, Ehrlich G, Veeh RH.  Biofilm-related infections of cerebrospinal fluid shunts.  Clin Microbiol Infect 12:331-337, 2006.

·         Hall-Stoodley L, Brun OS, Polshyna G, Barker LP.  Mycobacterium marinum biofilm formation reveals cording morphology.  FEMS Microbiol Lett  257:43-49, 2006.

·         Buchinsky FJ, Carter JJ, Wipf GC, Hughes JP, Koutsky LA, Galloway DA.  Comparison of oral fluid and serum ELISAs in the determination of IgG response to natural human papillomavirus infection in university women.  J Clin Virol 35:450-453, 2006.

·         Allegrucci M, Hu FZ, Shen K, Hayes J, Ehrlich GD, Post JC, Sauer K.  Phenotypic characterization of Streptococcus pneumoniae biofilm development.  J Bacteriol 188;7:2325-2335, 2006.  Full article 

·         Hall-Stoodley L, Watts G, Crowther JE, Balagopal A, Torrelles JB, Robison-Cox J, Bargatze RF, Harmsen AG, Crouch EC, Schlesinger LS.  Mycobacterium tuberculosis binding to human surfactant proteins A and D, fibronectin, and small airway epithelial cells under shear conditions.  Infect Immun 74;6:3587-3596, 2006.

·         Hall-Stoodley L, Hu FZ, Gieseke A, Nistico L, Nguyen D, Hayes J, Forbes M, Greenberg DP, Dice B, Burrows A, Wackym PA, Stoodley P, Post JC, Ehrlich G, Kerschner JE.  Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media.  JAMA 296;2:202-211, 2006.  Full article 

·         Sherwood ML, Buchinsky FJ, Quigley MR, Donfack J, Choi SS, Conley SF, Derkay CS, Myer CM III, Ehrlich GD, Post JC.  Unique challenges of obtaining regulatory approval for a multicenter protocol to study the genetics of RRP and suggested remedies.  Otolaryngol Head Neck Surg 135:189-196, 2006.

·         Donfack J, Buchinsky FJ, Derkay CS, Steinberg BM, Choi SS, Conley SF, Meyer CM III, McClay JE, Campisi P, Hu FZ, Preston RA, Abramson AL, Ehrlich GD, Post JC.  Four mutations in epidermodysplasia verruciformis 1 (EVER1) gene are not contributors to susceptibility in RRP.  Int J Pediatr Otorhinolaryngol 70:1235-1240, 2006.

·         Kathju S, Satish L, Rabik C, Rupert T, Oswald D, Johnson S, Hu FZ, Post JC, Ehrlich GD.  Identification of differentially expressed genes in scarless wound healing utilizing polymerase chain reaction-suppression subtractive hybridization.  Wound Rep Reg 14:413-420, 2006.

·         Satish L, Lyons-Weiler J, Hebda PA, Wells A.  Gene expression patterns in isolated keloid fibroblasts.  Wound Rep Reg 14:463-470, 2006.

·         Donfack J, Buchinsky FJ, Post JC, Ehrlich GD.  Human susceptibility to viral infection:  The search for HIV-protective alleles among Africans by means of genome-wide studies.  AIDS Res Hum Retroviruses 22;10:925-930, 2006.

·           Erdos G,  Sayeed S, Hu FZ, Antalis PT, Shen K, Hayes JD, Ahmed AI, Johnson SL, Post JC, Ehrlich GD.  Construction and characterization of a highly redundant Pseudomonas aeruginosa genomic library prepared from 12 clinical isolates:  Application to studies of gene distribution among populations.  Int J Pediatr Otorhinolaryngol 70:1891-1900, 2006.

·         Shen K, Sayeed S, Antalis P, Gladitz J, Ahmed A, Dice B, Janto B, Dopico R, Keefe R, Hayes J, Johnson S, Yu S, Ehrlich N, Jocz J, Kropp L, Wong R, Wadowsky RM, Slifkin M, Preston RA, Erdos G, Post JC, Ehrlich GD, Hu FZ.  Extensive genomic plasticity in Pseudomonas aeruginosa revealed by identification and distribution studies of novel genes among clinical isolates.  Infect Immun 74(9):5272-5283, 2006. Full article 

·         Singh MK, Scott TF, LaFramboise WA, Hu FZ, Post JC, Ehrlich GD.  Gene expression changes in peripheral blood mononuclear cells from multiple sclerosis patients undergoing $-interferon therapy.  J Neurol Sci, 258:52-59, 2007.

·         Hogg JS, Hu FZ, Janto B, Boissy R, Hayes J, Keefe R, Post JC, Ehrlich GD.  Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains.  Genome Biology 8;6:R103, 2007.   Full article 

·         Mu$mann M, Hu FZ, Richter M, de Beer D, Preisler A, Jørgensen BB, Huntermann M, Glöckner FO, Amann R, Koopman WJH, Lasken RS, Janto B, Hogg J, Stoodley P, Boissy R, Ehrlich GD.  Insights into the genome of large sulfur bacteria revealed by analysis of single filaments.  PLoS Biology 5(9)e230:1923-1937, 2007. Full article 

·         Buchinsky FJ, Forbes ML, Hayes JD,  Shen K, Ezzo S, Compliment J, Hogg J, Hiller NL, Hu FZ, Post JC, Ehrlich GD.  Virulence phenotypes of low-passage clinical isolates of nontypeable Haemophilus influenzae assessed using the chinchilla laniger model of otitis media.  BMC Microbiology 7:56, 2007. Full article 

·         Post JC, Hiller NL, Nistico L, Stoodley P, Ehrlich GD.  The role of biofilms in otolaryngologic infections:  Update 2007.  Curr Opin Otolaryngol Head Neck Surg 15;5:347-351, 2007. Full article 

·         Hiller NL, Janto B, Hogg JS, Boissy R, Yu S, Powell E, Keefe R, Ehrlich NE, Shen K, Hayes J, Barbadora K, Klimke W, Dernovoy D, Tatusova T, Parkhill J, Bentley SD, Post JC, Ehrlich GD, Hu FZ.  Comparative genomic analyses of seventeen Streptococcus pneumoniae strains:  Insights into the pneumococcal supragenome.  J Bacteriol 189(22):8186-8195, 2007.  Full article 

·         Palmer RJ, Stoodley P.  Biofilms 2007:  Broadened horizons and new emphases (Meeting Review).  J Bacteriol 189(22):7948-7960, 2007.

·         Kirisits MJ, Margolis JJ, Purevdorj-Gage BL, Vaughan B, Chopp DL, Stoodley P, Parsek MR.  Influence of the hydrodynamic environment on quorum sensing in Pseudomonas aeruginosa biofilms.  J Bacteriol 189(22):8357-8360, 2007.

·         Stoodley P, Nguyen D, Longwell M, Nistico L, von Ohle C, Milanovich N, de Jager M.  Effect of the Sonicare FlexCare power toothbrush on fluoride delivery through Streptococcus mutans biofilms.   Compend Contin Educ Dent 28(9):15-22, 2007.

·         Hu FZ, Ehrlich GD.  Population-level virulence factors amongst pathogenic bacteria:  Relation to infection outcome.  Future Microbiol, 3(1):31-42, 2008.  Full article 

·         Forbes ML, Horsey E, Hiller NL, Buchinsky FJ, Hayes JD, Compliment JM, Hillman T, Ezzo S, Shen K, Keefe R, Barbadora K, Post JC, Hu FZ, Ehrlich GD.  Strain-specific virulence phenotypes of Streptococcus pneumoniae assessed using the Chinchilla laniger model of otitis media.  PLoS One 3;4:e1969, 2008. Full article 

·         Stoodley P, Nistico L, Johnson S, Lasko LA, Baratz M, Gahlot V, Ehrlich GD, Kathju S.   Direct demonstration of viable S. aureus biofilms in an infected total joint arthroplasty.  J Bone Joint Surg Am, In press, 2008.

·         Satish L, Abdulally A, Oswald D, Johnson S, Hu FZ, Post JC, Ehrlich GD, Kathju S.  Differential expression of chaperonin containing T-complex polypeptide (CCT) subunits during fetal and adult skin wound healing. Cell Stress Chaperones, In press, 2008.

·         Satish L, LaFramboise WA, O’Gorman DB, Johnson S, Janto B, Gan BS, Baratz ME, Hu FZ, Post JC, Ehrlich GD, Kathju S.  Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren’s contracture.  BMC Med Genomics, In press, 2008.

·         Kerschner JE, Horsey E, Ahmed A, Erbe C, Khampang P, Cioffi J, Hu FZ, Post JC, Ehrlich GD.  Gene expression differences in infected and non-infected middle ear cDNA libraries.  Arch Otolaryngology Head Neck Surg, In press, 2008.

 

 



Back

 

 

 


About Us | Research | Education | Facilities | Faculty/Staff
Contact Us | Site Map | Help | Disclaimer | Contact Webmaster

Copyright © 2001 West Penn Allegheny Health System. All rights reserved.

Site development provided by H2 Design Group Inc.