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 The
Center for Genomic Sciences (CGS) is a comprehensive and flexible research
facility designed to investigate a broad range of medically and surgically
relevant problems using cutting-edge molecular genetic and bioinformatics
techniques. CGS is a self-contained research unit of Allegheny-Singer
Research Institute, ASRI, the research arm of Allegheny General Hospital
which, in turn, serves as the tertiary care facility for the entire West Penn Allegheny
Health System. The facilities and intellectual infrastructure of CGS
provides a collegial and collaborative academic/clinical environment that
promotes interdisciplinary research grounded in the fundamental concepts of
modern functional genomics. The Center fosters the development of surgeon-scientists,
physician-scientists and biomedical researchers throughout the institution
and the Pittsburgh area by actively working to develop partnerships among
teams of individuals with diverse scientific, clinical, computational and
engineering backgrounds. CGS scientists study genetic and evolutionary
phenomena that impact human health from a top-down approach. This is
accomplished by the use of global research tools which permit imaging of
entire genomes and expressomes simultaneously, as opposed to narrowly
investigating a single gene in isolation from its environment. This is the
molecular biological equivalent of studying a symphony from a conductor's
score instead of just listening to the second oboe to try to discern what
the composer had in mind. This approach to learning and understanding is
applied to viral and bacterial pathogens as well as to their human hosts.
Click below to learn more:
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New: Postdoctoral and Research Associate Positions
Available. Please click for application
details.
CGS SEMINAR
SERIES
Dr. Rob Knight
May 12, 2008
New Research Initiative at CGS:
CGS scientists led by Drs. Fen Ze Hu and Garth D. Ehrlich establish a
"Biomass to Fuels" program based on the microbiome of the Yak
gut in collaboration with Professors Dong Xiu Zhu and Gao Fu of the
Faculty of the Institute of Microbiology at the Chinese Academy of
Beijing.
CGS scientists, headed by Center Director Dr. Garth Ehrlich, have begun
a wide-ranging collaboration with scientists at the Max Plank Institute
in Bremen Germany to sequence the genomes of a number of unculturable
microbes thought to be important in global energy cycles. As part of
this collaboration a grant proposal has been submitted to the Joint
Genome Institute of the Department of Energy.
ASRI research leadership announces the creation of a new research
facility. Drs. J. Christopher Post and Garth D. Ehrlich have
established the Allegheny Human Performance Laboratory (AHPL) to study
the genetic bases of human performance. Initial efforts will be focused
on finding the genes associated with resistance to sleep deprivation
and fatigue. Funding requests have been made with the United States
Departments of Defense and Transportation to launch this new facility.
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